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Caitlin Lienkaemper

Picture of Caitlin Lienkaemper.

Thesis

Toric Ideals, Polytopes, and Convex Neural Codes

Advisor
Mohamed Omar
Second Reader(s)
Dagan Karp

Abstract

How does the brain encode the spatial structure of the external world? A partial answer comes through place cells, hippocampal neurons which become associated to approximately convex regions of the world known as their place fields. When an organism is in the place field of some place cell, that cell will fire at an increased rate. A neural code describes the set of firing patterns observed in a set of neurons in terms of which subsets fire together and which do not. If the neurons the code describes are place cells, then the neural code gives some information about the relationships between the place fields--for instance, two place fields intersect if and only if their associated place cells fire together. Since place fields are convex, we are interested in determining which neural codes can be realized with convex sets and in finding convex sets which generate a given neural code when taken as place fields. To this end, we study algebraic invariants associated to neural codes, such as neural ideals and toric ideals. We work with a special class of convex codes, known as inductively pierced codes, and seek to identify these codes through the Gröbner bases of their toric ideals.

Additional Materials

Poster